6-ethynyl-2,2-difluoro-spiro[2.5]octane CAS 2306272-57-9
| CAS No. | 2306272-57-9 |
| Molecular Formula | C10H12F2 |
| Molecular Weight | 170.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 170.20 g/mol gives 6-ethynyl-2,2-difluoro-spiro[2.5]octane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-ethynyl-2,2-difluoro-spiro[2.5]octane (CAS 2306272-57-9), molecular formula C10H12F2 and molecular weight 170.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine substitution, an aromatic ring system, 6-ethynyl-2,2-difluoro-spiro[2.5]octane is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 170.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-ethynyl-2,2-difluoro-spiro[2.5]octane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12F2 |
| Molecular Weight | 170.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
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- S-(4-Fluorophenyl) ethanethioate (CAS 42467-05-0)
- ethyl 8-fluoroimidazo[1,5-a]pyridine-5-carboxylate (CAS 2021235-74-3)
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- 5H-Thiochromeno[2,3-b]pyridin-5-one (CAS 5698-68-0)
- 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile (CAS 1638764-76-7)
- 4-([4-(Propan-2-yl)-4h-1,2,4-triazol-3-yl]methyl)piperidine (CAS 1517340-55-4)
- 3-Bromo-1-methyl-1H-indole-2-carbonitrile (CAS 154379-83-6)
- Ethyl 5-chloro-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate (CAS 288252-75-5)
- 2-Amino-3-(4-bromo-1H-pyrazol-1-yl)propanenitrile (CAS 1249444-29-8)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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