Tert-butyl (4,4-difluoropiperidin-3-yl)(methyl)carbamate CAS 2306274-44-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl (4,4-difluoropiperidin-3-yl)(methyl)carbamate.

Tert-butyl (4,4-difluoropiperidin-3-yl)(methyl)carbamate (CAS 2306274-44-0), molecular formula C11H20F2N2O2 and molecular weight 250.29 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl (4,4-difluoropiperidin-3-yl)(methyl)carbamate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 250.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Tert-butyl (4,4-difluoropiperidin-3-yl)(methyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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