Tert-butyl 9-amino-1,1-difluoro-3-azaspiro[5.5]Undecane-3-carboxylate CAS 2306274-65-5
| CAS No. | 2306274-65-5 |
| Molecular Formula | C15H26F2N2O2 |
| Molecular Weight | 304.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Tert-butyl 9-amino-1,1-difluoro-3-azaspiro[5.5]Undecane-3-carboxylate (CAS 2306274-65-5), molecular formula C15H26F2N2O2 and molecular weight 304.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 9-amino-1,1-difluoro-3-azaspiro[5.5]Undecane-3-carboxylate (C15H26F2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H26F2N2O2 |
| Molecular Weight | 304.38 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-aminospiro[chromane-2,3'-pyrrolidine]-1'-carboxylate (CAS 2137917-15-6)
- Tert-butyln-[(3r)-spiro[3h-benzofuran-2,4'-piperidine]-3-yl]carbamate (CAS 2377357-01-0)
- tert-butyl 4-[2-oxo-2-(pyridin-3-yl)ethyl]piperidine-1-carboxylate (CAS 791064-62-5)
- Tilisolol (CAS 85136-71-6)
- 1-Allyl-7-(methylthio)-1H-pyrimido-[4,5-d][1,3]oxazine-2,4-dione (CAS 1253791-06-8)
- Tert-butyl (2-chloro-5-(trifluoromethyl)phenyl)carbamate (CAS 1260834-16-9)
- 3-(3-(M-tolyl)propanoyl)benzonitrile (CAS 898790-45-9)
- 6-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 933752-89-7)
- Guanosine 3',5'-Cyclic Monophosphate Sodium Salt (CAS 40732-48-7)
- PD 168077 maleate, 98% (CAS 190383-31-4)
- 2,3-Dimethyl-1-[3-(methylsulfanyl)phenyl]-1,4-dihydropyridin-4-one (CAS 861210-59-5)
- 4,5-Dimethylisatin (CAS 100487-79-4)
- Methyl 2-oxopiperidine-3-carboxylate (CAS 106118-94-9)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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