Tert-butyl 8-amino-4,4-difluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2306275-45-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2306275-45-4
Molecular FormulaC14H18F2N2O2
Molecular Weight284.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 8-amino-4,4-difluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2306275-45-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Tert-butyl 8-amino-4,4-difluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 2306275-45-4) is a high-purity analytical reference standard with the molecular formula C14H18F2N2O2 and a molecular weight of 284.30 g/mol.

Based on its molecular formula C14H18F2N2O2, Tert-butyl 8-amino-4,4-difluoro-3,4-dihydroisoquinoline-2(1H)-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H18F2N2O2
Molecular Weight284.30 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF-containing
Nitrogen Atoms2

Recommended Standards

Why CATO?