3-Bromo-5-fluoro-1-(phenylsulfonyl)-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1H-pyrrolo[2,3-b]pyridine CAS 2306276-23-1
| CAS No. | 2306276-23-1 |
| Molecular Formula | C19H18BrFN2O4S |
| Molecular Weight | 469.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-5-fluoro-1-(phenylsulfonyl)-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2306276-23-1) is a high-purity analytical reference standard with the molecular formula C19H18BrFN2O4S and a molecular weight of 469.32 g/mol.
The molecular framework of 3-Bromo-5-fluoro-1-(phenylsulfonyl)-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1H-pyrrolo[2,3-b]pyridine (C19H18BrFN2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Bromo-5-fluoro-1-(phenylsulfonyl)-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-1H-pyrrolo[2,3-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18BrFN2O4S |
| Molecular Weight | 469.32 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Ethyl 2,3,4,5-tetrafluorobenzoate (CAS 122894-73-9)
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- 2-(4-Cyclohexylpiperazin-1-yl)benzo[d]thiazole (CAS 790645-69-1)
- (S)-3-Amino-3-(4-fluorophenyl)propan-1-ol (CAS 228422-49-9)
- 4-(2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)benzamide (CAS 477329-01-4)
- 1-Morpholino-2-(piperazin-1-yl)ethanone (dihydrochloride) (CAS 300704-06-7)
- N-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]-N'-(3-methoxyphenyl)urea (CAS 256471-20-2)
- (2,3,5-Trifluorophenyl)hydrazine hydrochloride (CAS 1909312-01-1)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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