Tert-butyl 3-bromo-2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate CAS 2306277-84-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2306277-84-7
Molecular FormulaC13H16BrClN2O2
Molecular Weight347.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 3-bromo-2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate CAS 2306277-84-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 347.64 g/mol gives Tert-butyl 3-bromo-2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tert-butyl 3-bromo-2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 2306277-84-7), molecular formula C13H16BrClN2O2 and molecular weight 347.64 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, Tert-butyl 3-bromo-2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (C13H16BrClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 347.64 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H16BrClN2O2
Molecular Weight347.64 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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