6-Fluoroindole-3-carboxylic Acid CAS 23077-44-3
| CAS No. | 23077-44-3 |
| Molecular Formula | C9H6FNO2 |
| Molecular Weight | 179.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Fluoroindole-3-carboxylic Acid (C9H6FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Fluoroindole-3-carboxylic Acid (CAS 23077-44-3) is a high-purity analytical reference standard with the molecular formula C9H6FNO2 and a molecular weight of 179.15 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6FNO2 |
| Molecular Weight | 179.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoroindole Standards
- 4-Fluoroindole-2-carboxylic Acid (CAS 399-68-8)
- 4-Fluoroindole-3-carboxylic Acid (CAS 23077-42-1)
- 4-Fluoroindole-6-carboxylic Acid (CAS 885520-31-0)
- 5-Fluoroindole-3-carboxylic Acid (CAS 23077-43-2)
- 6-Fluoroindole-2-carboxylic acid (CAS 3093-97-8)
- 7-Fluoroindole-3-carboxylic Acid (CAS 858515-66-9)
- 7-Fluoroindole-6-carboxylic Acid (CAS 908600-75-9)
- Methyl 4-Fluoroindole-3-carboxylate (CAS 1220039-52-0)
Recommended Standards
- 6-Fluoroisoquinoline-1,3(2H,4H)-dione (CAS 501130-46-7)
- 6-Fluoro-7-methylindoline-2,3-dione (CAS 57817-03-5)
- 6-Fluoroquinoline-2,4(1H,3H)-dione (CAS 2009563-91-9)
- 6-Fluoro-5-methylindoline-2,3-dione (CAS 749240-55-9)
- tert-butyl 3-oxo-2,4-dihydropyrido[3,4-b]pyrazine-1-carboxylate (CAS 1936127-34-2)
- 4-[Benzo(b)thiophen-2-yl]phenol (CAS 65540-08-1)
- (E)-3-methoxythiophene-2-carbaldehyde oxime (CAS 1824827-05-5)
- (S)-2-Amino-1-(3-((cyclopropylmethyl)amino)piperidin-1-yl)ethanone (CAS 1354007-42-3)
- 4,5-Dimethylphthalic acid (CAS 5680-10-4)
- 2-(3,5-Dichlorophenyl)-6-methylbenzo[d]thiazole (CAS 1242303-31-6)
- 6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridin-3-amine (CAS 1006464-86-3)
- Polygalasaponin XXXII (CAS 176182-04-0)
- N-[(1-Aminocyclopentyl)methyl]acetamide (CAS 904815-32-3)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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