4-(4-Chlorobenzyl)piperazin-2-one CAS 23099-66-3
| CAS No. | 23099-66-3 |
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Chlorobenzyl)piperazin-2-one (CAS 23099-66-3), molecular formula C11H13ClN2O and molecular weight 224.69 g/mol, is a CATO reference standard with documented purity and traceability.
4-(4-Chlorobenzyl)piperazin-2-one (C11H13ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Chlorobenzyl)piperazin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzyl Standards
- (S)-3-(2-Chlorobenzyl)piperazin-2-one (CAS 1240583-37-2)
- (R)-3-(2-Chlorobenzyl)piperazin-2-one (CAS 1240586-57-5)
- (R)-3-(4-Chlorobenzyl)piperazin-2-one (CAS 1240586-96-2)
- (S)-3-(4-Chlorobenzyl)piperazin-2-one (CAS 1240590-34-4)
- 1-(3-Chlorobenzyl)piperazin-2-one (CAS 701208-30-2)
- 1-(4-Chlorobenzyl)piperazin-2-one (CAS 701208-33-5)
- 1-(4-Chlorobenzyl)tetrahydropyrimidin-2(1H)-one (CAS 34790-85-7)
- 3-(3-Chlorobenzyl)cyclobutanecarboxylic acid (CAS 1399659-85-8)
Recommended Standards
- 3-Chloro-4-[(pyrrolidin-1-yl)carbonyl]aniline (CAS 209959-69-3)
- 4-chloro-1-(3-methylbutan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 21301-86-0)
- 3-Chloro-4-(1-piperazinyl)-benzaldehyde (CAS 909418-74-2)
- 4-chloro-1-(pentan-3-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 21253-91-8)
- 3,4,5-Trifluorobenzohydrazide (CAS 1263064-36-3)
- PBI 344 (CAS 15764-81-5)
- 5-Bromo-2-(methylamino)pyridine (CAS 84539-30-0)
- N-Boc-2-(5-bromo-2-thienyl)ethanamine (CAS 885279-60-7)
- 6-[4,5-Dimethyl-2-thiazolyl]aminonicotinic Acid (CAS 1273946-12-5)
- N-(3-Acetyl-2-hydroxyphenyl)-4-(4-phenylbutoxy)benzamide (CAS 136450-06-1)
- 1-(2-Methoxy-5-methylphenyl)-1h-pyrazole-3-carboxylic acid (CAS 1152535-19-7)
- Posaconazole Impurity 60 (CAS CATO-C4X-120860)
- 4-methylenepiperidine (CAS 148133-82-8)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com