2-[5-Fluoro-2-methoxy-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2311855-36-2
| CAS No. | 2311855-36-2 |
| Molecular Formula | C14H17BF4O3 |
| Molecular Weight | 320.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[5-Fluoro-2-methoxy-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
2-[5-Fluoro-2-methoxy-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2311855-36-2) is a high-purity analytical reference standard with the molecular formula C14H17BF4O3 and a molecular weight of 320.09 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-[5-Fluoro-2-methoxy-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 320.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H17BF4O3 |
| Molecular Weight | 320.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-[5-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1079402-39-3)
- 2-(2-Fluoro-6-methoxy-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2890194-34-8)
- 2-(3-Fluoro-4-methoxy-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121513-13-9)
- 2-(7-Fluoro-3-iodo-1H-pyrrolo[3,2-c]pyridin-1-yl)propan-1-ol (CAS 1824056-47-4)
- Methyl 5-fluoro-3-iodo-1H-indazole-6-carboxylate (CAS 1227269-00-2)
- Methyl 5-fluoro-6-iodo-7H-pyrrolo[2,3-b]pyridine-4-carboxylate (CAS 1261365-57-4)
- Methyl 6-fluoro-3-iodo-1H-indazole-4-carboxylate (CAS 885521-81-3)
- 2-Fluoro-1-iodo-3-methoxy-4-(trifluoromethyl)benzene (CAS 2384557-91-7)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(4-(1,1,2,2-tetrafluoroethoxy)phenyl)-1,3,2-dioxaborolane (CAS 503309-12-4)
- 8-Iodo-1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione (CAS 5415-41-8)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(4-chlorophenyl)methanone (CAS 338953-54-1)
- 1-Allyl-3-(4-fluoro-2-iodophenyl)urea (CAS 1424538-68-0)
- Potassium (1-boc-4-piperidinylmethoxyoxy)methyltrifluoroborate (CAS 1823136-59-9)
- N-Benzyloxycarbonyl-O-mesyl-L-serine methyl ester (CAS 132249-34-4)
- 1-(2-Chloro-7H-purin-6-yl)piperidine-4-carboxylic acid (CAS 919736-51-9)
- Oseltamivir Impurity 104 (CAS 204254-92-2)
- Ethyl 3-(2-chlorobenzimidazol-1-yl)propanoate (CAS 299418-50-1)
- 1H-Pyrazole, 1-[2-methyl-3-(phenylmethoxy)propyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 1380304-51-7)
- 1H-Perfluorooct-1-ene (CAS 7621-51-4)
- 4-Hydroxy-6-methyl-3-(2-methylthiazol-4-yl)-2H-pyran-2-one (CAS 1295500-81-0)
- 1-Methyl-4-oxo-6-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 1217071-29-8)
- Semaglutide-d8 Tetratrifluoroacetate (CAS CATO-C4X-222617)
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