3,3-Difluoro-1-(1H-1,2,3-triazol-5-yl)cyclobutan-1-amine dihydrochloride CAS 2316459-16-0
| CAS No. | 2316459-16-0 |
| Molecular Formula | C6H8F2N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,3-Difluoro-1-(1H-1,2,3-triazol-5-yl)cyclobutan-1-amine dihydrochloride.
3,3-Difluoro-1-(1H-1,2,3-triazol-5-yl)cyclobutan-1-amine dihydrochloride (CAS 2316459-16-0), molecular formula C6H8F2N4HCl and molecular weight 210.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,3-Difluoro-1-(1H-1,2,3-triazol-5-yl)cyclobutan-1-amine dihydrochloride (C6H8F2N4HCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3,3-Difluoro-1-(1H-1,2,3-triazol-5-yl)cyclobutan-1-amine dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F2N4 2*HCl |
| Molecular Weight | 210.61 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Difluoro Standards
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Recommended Standards
- 8'-Bromo-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] (CAS 885269-37-4)
- 4-Cyclohexyl-benzenethiol (CAS 18325-50-3)
- (5-Amino-2-fluorophenyl)(4-methylpiperazin-1-yl)methanone (CAS 1156817-81-0)
- n-(2,6-Dimethylphenyl)benzo[d]thiazol-2-amine (CAS 54708-13-3)
- 1-(Pyrazin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1103848-03-8)
- Metoclopramide Impurity 85 (CAS 1882-76-4)
- Ethyl 2-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methylidene)-4,4,4-trifluoro-3-oxobutanoate (CAS 1823194-75-7)
- 2,4-Dimethoxy-6-methylpyrimidine-5-carboxylic acid (CAS 106852-32-8)
- Tert-butyl 4-aminoadamantane-1-carboxylate (CAS 2248383-62-0)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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