Methyl 5-chloro-7-(hydroxymethyl)-1H-indole-4-carboxylate CAS 2316684-50-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2316684-50-9
Molecular FormulaC11H10ClNO3
Molecular Weight239.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 5-chloro-7-(hydroxymethyl)-1H-indole-4-carboxylate CAS 2316684-50-9 chemical structure

Description

Methyl 5-chloro-7-(hydroxymethyl)-1H-indole-4-carboxylate (CAS 2316684-50-9) is a high-purity analytical reference standard with the molecular formula C11H10ClNO3 and a molecular weight of 239.66 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl 5-chloro-7-(hydroxymethyl)-1H-indole-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 5-chloro-7-(hydroxymethyl)-1H-indole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H10ClNO3
Molecular Weight239.66 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentCl-containing
Nitrogen Atoms1

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