4-Aminobenzoic Acid EP Impurity B HCl CAS 23239-88-5

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.23239-88-5
Molecular FormulaC9H11NO2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

4-Aminobenzoic Acid EP Impurity B HCl CAS 23239-88-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 201.65 g/mol gives 4-Aminobenzoic Acid EP Impurity B HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-Aminobenzoic Acid EP Impurity B HCl (CAS 23239-88-5), a pharmacopoeial impurity reference standard (molecular formula C9H11NO2HCl, MW 201.65 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of 4-Aminobenzoic Acid EP Impurity B HCl (C9H11NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), 4-Aminobenzoic Acid EP Impurity B HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H11NO2 HCl
Molecular Weight201.65 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Halogen ContentCl-containing
Nitrogen Atoms1

Related Aminobenzoic Standards

Recommended Standards

Why CATO?