3-Fluoromethyl-piperazine-1-carboxylic acid tert-butyl ester hydrochloride CAS 2331259-80-2
| CAS No. | 2331259-80-2 |
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Fluoromethyl-piperazine-1-carboxylic acid tert-butyl ester hydrochloride (CAS 2331259-80-2) is a high-purity analytical reference standard with the molecular formula C10H19FN2O2HCl and a molecular weight of 254.73 g/mol.
3-Fluoromethyl-piperazine-1-carboxylic acid tert-butyl ester hydrochloride (C10H19FN2O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Fluoromethyl-piperazine-1-carboxylic acid tert-butyl ester hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H19FN2O2 HCl |
| Molecular Weight | 254.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluoromethyl Standards
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- (S)-2-(fluoromethyl)-1-methylpiperazine (CAS 1033719-13-9)
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Recommended Standards
- 8-(tert-Butyl) 2-methyl 1-oxo-8-azaspiro[4.5]decane-2,8-dicarboxylate (CAS 849203-09-4)
- ethyl 3-(pyrrolidin-2-yl)-1H-1,2,4-triazole-5-carboxylate (CAS 1530839-86-1)
- N-(Trimethylsilyl)methanesulfonamide (CAS 999-96-2)
- (2-Methylenecyclohexyl)methanol (CAS 78426-32-1)
- Sepiapterin Impurity 11 (CAS 1177884-36-4)
- Regorafenib Impurity 4 (CAS 1187945-05-6)
- 3-(Aminomethyl)-5-bromo-2-(difluoromethyl)pyridin-4-amine (CAS 1806805-23-1)
- (4-Bromophenyl)(3-phenyloxiran-2-yl)methanone (CAS 29425-81-8)
- 4-(Difluoromethyl)benzo[d]oxazol-2-amine (CAS 1806547-40-9)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
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