4-Oxo-4H-benzo[h]chromene-3-carbaldehyde CAS 23469-48-9

Purity 97%+In StockPharmaceutical Standards
CAS No.23469-48-9
Molecular FormulaC14H8O3
Molecular Weight224.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Oxo-4H-benzo[h]chromene-3-carbaldehyde CAS 23469-48-9 chemical structure

Description

The occurrence of 4-Oxo-4H-benzo[h]chromene-3-carbaldehyde is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Oxo-4H-benzo[h]chromene-3-carbaldehyde (CAS 23469-48-9), molecular formula C14H8O3 and molecular weight 224.21 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Oxo-4H-benzo[h]chromene-3-carbaldehyde (C14H8O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H8O3
Molecular Weight224.21 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963

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