Methylene Blue Impurity 13 Chloride CAS 23481-50-7
| CAS No. | 23481-50-7 |
| Molecular Formula | C18H22N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Methylene Blue Impurity 13 Chloride (CAS 23481-50-7, C18H22N3SCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Methylene Blue Impurity 13 Chloride (C18H22N3SCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 347.90 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Methylene Blue Impurity 13 Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22N3S Cl |
| Molecular Weight | 347.90 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylene Standards
- γ-Methylene-γ-butyrolactone (CAS 10008-73-8)
- 4,4＇-Methylene-Bis(2-chloroaniline) (CAS 101-14-4)
- 5-Methylene-2-phenyl-1,3-dioxolan-4-one (CAS 101822-11-1)
- 2-Methylene-1,3,6-trioxocane (CAS 105649-50-1)
- 6-Methyl-3-methylene-3,4-dihydroquinoxalin-2(1H)-one (CAS 106480-88-0)
- 5-Methylene-2(5H)-furanone (CAS 108-28-1)
- 3-(2-Methylene-4-phenylbutanoyl)oxazol-2(3H)-one (CAS 1151767-07-5)
- (Methylene-d2)gibberellin A5 (CAS 120396-32-9)
Recommended Standards
- Rivaroxaban Impurity 155 (CAS CATO-C4X-1090155)
- Thiamine /Vitamin B1 Impurity 40 (CAS CATO-C4X-187340)
- Luliconazole impurity 29 (CAS CATO-C4X-285329)
- 4-Amino-N-(3-methoxypropyl)benzenesulfonamide (CAS 27678-19-9)
- Methyl 3-fluoro-4-hydroxy-5-nitrobenzoate (CAS 850335-27-2)
- 2-(4-Acetylphenyl)propanoic Acid (CAS 41387-29-5)
- N-(3-cyanobenzyl)-N-cyclopropylglycine (CAS 1184140-78-0)
- 2-(aminooxy)-2-cyclopropylacetic acid hydrochloride (CAS 2060053-07-6)
- 4-Bromo-6-(difluoromethyl)-5-fluoropyridin-2-ol (CAS 1805392-76-0)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com