Vildagliptin impurity 12 CAS 23500-10-9
| CAS No. | 23500-10-9 |
| Molecular Formula | C7H10ClNO3 |
| Molecular Weight | 191.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vildagliptin impurity 12 (CAS 23500-10-9, C7H10ClNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Vildagliptin impurity 12 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Vildagliptin impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10ClNO3 |
| Molecular Weight | 191.61 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Vildagliptin Standards
- Vildagliptin Impurity 101 (CAS 23500-11-0)
- Vildagliptin Impurity (CAS CATO-C1911319)
- Vildagliptin Impurity 59 (CAS 214398-99-9)
- Vildagliptin Impurity 60 (CAS 1211679-98-9)
- Vildagliptin Impurity 92 (CAS 53990-71-9)
- Vildagliptin Impurity 39 (CAS 6708-06-1)
- Vildagliptin Impurity 40 (CAS 19943-27-2)
- Vildagliptin Impurity 62 (CAS 39917-38-9)
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