Fmoc-2-amino-5-phenyl(2,6-Difluoro)-L-pentanoic acid CAS 2350135-28-1
| CAS No. | 2350135-28-1 |
| Molecular Formula | C26H23F2NO4 |
| Molecular Weight | 451.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fmoc-2-amino-5-phenyl(2,6-Difluoro)-L-pentanoic acid.
Fmoc-2-amino-5-phenyl(2,6-Difluoro)-L-pentanoic acid (CAS 2350135-28-1) is a high-purity analytical reference standard with the molecular formula C26H23F2NO4 and a molecular weight of 451.46 g/mol.
The molecular framework of Fmoc-2-amino-5-phenyl(2,6-Difluoro)-L-pentanoic acid (C26H23F2NO4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Fmoc-2-amino-5-phenyl(2,6-Difluoro)-L-pentanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H23F2NO4 |
| Molecular Weight | 451.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-2-amino-5-phenyl(2,3-Difluoro)-L-pentanoic acid (CAS 2349313-65-9)
- Fmoc-2-amino-5-phenyl(2,5-Difluoro)-L-pentanoic acid (CAS 2350817-95-5)
- Fmoc-2-amino-5-phenyl(3,4-Difluoro)-L-pentanoic acid (CAS 2350133-60-5)
- Fmoc-(S)-3-Amino-4-(2-naphthyl)-butyric acid (CAS 1186216-21-6)
- N-Fmoc-N-methyl-3-(1-naphthyl)-L-alanine (CAS 1380327-68-3)
- Fmoc-N-methyl-3-(2-naphthyl)-D-alanine (CAS 179385-30-9)
- (S)-3-(Fmoc-amino)-4-(2-naphthyl)butyric acid (CAS 270063-40-6)
- Fmoc-(R)-3-amino-4-(1-naphthyl)-butyric acid (CAS 269398-89-2)
Recommended Standards
- N-(1-(4-ethylphenyl)-3-(4-(2-fluorophenyl)piperazin-1-yl)-3-oxopropyl)-2,2,2-trifluoroacetamide (CAS 866019-26-3)
- 3-Amino-N-cyclopropyl-6-(3,4-dimethoxybenzyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 924832-28-0)
- Flucythrinate (CAS 70124-77-5)
- 3-Amino-N-(3,4-dimethoxybenzyl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 664999-37-5)
- 3-Chloro-4,5-dimethoxy-N-methylbenzamide (CAS 827012-30-6)
- 1-(3-Nitrophenyl)-3-phenylprop-2-en-1-one (CAS 16619-21-9)
- 2-(5-Amino-3-cyclopropyl-4-nitro-1H-pyrazol-1-yl)ethanol (CAS 1707603-28-8)
- 2-Methylbenzoxazol-4-ol (CAS 51110-60-2)
- L-Fucitol (CAS 13074-06-1)
- 3-(3-piperidyl)prop-2-ynoic acid (CAS 1896500-27-8)
- 2-Propyl-2,4-pentadienoic Acid (CAS 72010-18-5)
- N-(2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-fluorobenzenesulfonamide (CAS 2098632-64-3)
- 5-Amino-N-cyclopropyl-2-methoxybenzene-1-sulfonamide (CAS 1041593-92-3)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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