((1R,2S)-2-(3-fluorophenyl)cyclopropyl)methanamine CAS 2351225-61-9
| CAS No. | 2351225-61-9 |
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies ((1R,2S)-2-(3-fluorophenyl)cyclopropyl)methanamine (CAS 2351225-61-9), a certified reference material (molecular formula C10H12FN, MW 165.21 g/mol) for analytical method development and quality control.
The molecular framework of ((1R,2S)-2-(3-fluorophenyl)cyclopropyl)methanamine (C10H12FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- ((1R,2R)-2-(3-fluorophenyl)cyclopropyl)methanamine (CAS 928121-24-8)
- (oxolan-2-yl)methanesulfonamide (CAS 859998-68-8)
- Spiro[cyclopropane-1,6'-thieno[2,3-c]pyrrol]-4'(5'H)-one (CAS 1951483-75-2)
- (R)-1-(1-Hydroxyethyl)cyclopropane-1-sulfonamide (CAS 2490187-94-3)
- 4-(Methyl(propyl)amino)benzaldehyde (CAS 1078-18-8)
- 4-phenoxybenzenesulfonyl chloride (CAS 1623-92-3)
- 1-[2-(Benzylsulfanyl)ethyl]-3-(2-methylcyclohexyl)urea (CAS 1007818-44-1)
- 8,9,11-Trimethylbenz[a]anthracene (CAS 74845-58-2)
- 3-Benzamido-N-[(4-fluorophenyl)methyl]thiophene-2-carboxamide (CAS 439120-54-4)
- Adenosine 5＇-Monophosphate Disodium Salt (CAS 4578-31-8)
- Bumetanide Impurity 65 (CAS CATO-C4X-198665)
- 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic Acid (CAS 1233332-37-0)
- 1-(8-Chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)ethanone (CAS 19686-26-1)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
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