1-(3-Aminophenyl)-2,2,2-trifluoroethan-1-one CAS 23516-80-5
| CAS No. | 23516-80-5 |
| Molecular Formula | C8H6F3NO |
| Molecular Weight | 189.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(3-Aminophenyl)-2,2,2-trifluoroethan-1-one (CAS 23516-80-5), molecular formula C8H6F3NO and molecular weight 189.13 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H6F3NO, 1-(3-Aminophenyl)-2,2,2-trifluoroethan-1-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 189.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(3-Aminophenyl)-2,2,2-trifluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6F3NO |
| Molecular Weight | 189.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Aminophenyl Standards
- 1-(2-Aminophenyl)-2,2,2-trifluoroethan-1-one (CAS 351002-89-6)
- 1-(4-Aminophenyl)-2,2,2-trifluoroethanone (CAS 23516-79-2)
- 3-Aminophenyl dihydrogen phosphate (CAS 881201-93-0)
- 4-AMINOPHENYL HYDROGEN SULFATE (CAS 15658-52-3)
- 1-(4-Aminophenyl)-5-methyl-1H-pyrazol-3(2H)-one (CAS 114306-97-7)
- Ethyl 3-(2-aminophenyl)prop-2-ynoate (CAS 116659-85-9)
- 1-(2-Aminophenyl)-5-methyl-2,3-dihydro-1h-imidazol-2-one (CAS 1208528-11-3)
- 1-(3-Aminophenyl)-5-methyl-2,3-dihydro-1h-imidazol-2-one (CAS 1211122-33-6)
Recommended Standards
- 1-(3-(Trifluoromethyl)pyridin-2-yl)ethan-1-one (CAS 749257-78-1)
- 1-(4-(Trifluoromethyl)pyridin-3-yl)ethanone (CAS 955997-27-0)
- (E)-2-(Trifluoromethyl)benzaldehyde oxime (CAS 24652-61-7)
- 1-(5-(Trifluoromethyl)pyridin-3-yl)ethanone (CAS 944904-85-2)
- Trimethylsilyl 2-((methoxycarbonothioyl)(methyl)amino)acetate (CAS 34653-82-2)
- Cyproterone Acetate (CAS 427-51-0)
- N-(2-(piperidin-1-yl)ethyl)cycloheptanamine (CAS 416869-47-1)
- 1-(4-Cyanophenyl)-1H-imidazole-4-carboxylic acid (CAS 1239723-51-3)
- 7-Chloro-6-fluoro-3-((4-methoxybenzyl)oxy)quinolin-2-amine (CAS 2435612-29-4)
- 3,3,5,5-Tetramethylcyclohexanone (CAS 14376-79-5)
- Pomalidomide-CO-PEG2-propargyl (CAS 2243000-25-9)
- (Arg8,Gly10,Lys11,Arg12)-Vasotocin (CAS 122842-47-1)
- 4-[4-chloro-2-(dimethylamino)-1,3-thiazol-5-yl]but-3-en-2-one (CAS 1344869-08-4)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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