1-(3-Fluoro-4-methoxyphenyl)propan-2-one CAS 2357-79-1
| CAS No. | 2357-79-1 |
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(3-Fluoro-4-methoxyphenyl)propan-2-one (C10H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-(3-Fluoro-4-methoxyphenyl)propan-2-one (CAS 2357-79-1), a certified reference material (molecular formula C10H11FO2, MW 182.19 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-(4-Fluoro-3,5-dimethylphenyl)acetic acid (CAS 1000544-58-0)
- 1-(5-Fluoro-2-methoxyphenyl)propan-2-one (CAS 1017082-10-8)
- 3-(3-Fluoro-5-methylphenyl)propanoic acid (CAS 1017779-56-4)
- 3-Fluoro-4-(propan-2-yloxy)benzaldehyde (CAS 1021231-72-0)
- 3-(3-fluoro-4-methoxyphenyl)propanal (CAS 1036396-31-2)
- 3-Fluoro-2-isopropoxybenzaldehyde (CAS 1037092-98-0)
- Ethyl 3-Fluoro-2-methylbenzoate (CAS 114312-57-1)
- 2-(3-Fluoro-4-methoxyphenyl)-2-methyloxirane (CAS 1189785-35-0)
Recommended Standards
- 1-(3-Fluoro-4-methoxyphenyl)-1-propanone (CAS 586-22-1)
- 1-(4-Ethoxy-2-fluorophenyl)ethanone (CAS 851667-22-6)
- 1-(3-Fluoro-4-hydroxyphenyl)-2-methylpropan-1-one (CAS 879339-65-8)
- 1-(4-Fluoro-2-methoxyphenyl)propan-1-one (CAS 231958-06-8)
- (S)-2-((S)-2-amino-4-methylpentanamido)hexanamide hydrochloride (CAS 68759-98-8)
- 1-(3-Amino-2,6-dichloropyridin-4-yl)ethanone (CAS 912772-91-9)
- (2-Ethyl-4-fluorophenyl)boronic acid (CAS 1446716-65-9)
- 2-Chloro-4-ethynyl-7H-pyrrolo[2,3-d]pyrimidine 1147014-54-7 A1-00647 (CAS 1147014-54-7)
- 2-(3-Bromoadamantan-1-yl)acetic acid (CAS 17768-34-2)
- 2-Chloro-5-(n-(4-iodophenyl)sulfamoyl)benzoic acid (CAS 380432-24-6)
- Axitinib Impurity 27 (CAS CATO-C4X-107127)
- Methyl 3-bromo-2,5-dichlorobenzoate (CAS 933585-62-7)
- Aliskiren (CAS 173334-57-1)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com