Thalidomide-C3-O-C2-amine HCl CAS 2357109-64-7
| CAS No. | 2357109-64-7 |
| Molecular Formula | C18H21N3O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Thalidomide-C3-O-C2-amine HCl (CAS 2357109-64-7), molecular formula C18H21N3O5HCl and molecular weight 395.84 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Thalidomide-C3-O-C2-amine HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 395.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Thalidomide-C3-O-C2-amine HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21N3O5 HCl |
| Molecular Weight | 395.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Thalidomide Standards
- Thalidomide-propargyl-OH (CAS 1216805-67-2)
- Thalidomide-d4 (CAS 1219177-18-0)
- Thalidomide Impurity 3 (CAS 126663-38-5)
- Thalidomide-5,6-F (CAS 1496997-41-1)
- Thalidomide-O-amido-C4-NH2 (CAS 1799711-24-2)
- Thalidomide-O-amido-C3-PEG3-C1-NH2 (CAS 1799711-29-7)
- Thalidomide-O-amido-C6-NH2 (CAS 1950635-13-8)
- Thalidomide-O-amido-C6-NH2 (TFA) (CAS 1950635-14-9)
Recommended Standards
- 8-Bromo-5-methoxyquinolin-4(1H)-one (CAS 643069-40-3)
- 3-Methyl-5-oxo-5-(4-n-propylphenyl)valeric acid (CAS 951893-49-5)
- 2-(tert-Butyl)-3-cyclopropoxy-5-methoxypyridine (CAS 1243409-09-7)
- 1-Bromo-4-butoxy-2-fluorobenzene (CAS 155854-29-8)
- (2-Amino-5-cyanophenyl)boronic acid (CAS 1374334-76-5)
- 2-Amino-7-bromoquinoline-3-carbaldehyde (CAS 2500655-31-0)
- 4-Acetamidobenzenesulfinic Acid Sodium Salt (CAS 15898-43-8)
- 3-((6-Isopropylpyrimidin-4-yl)amino)propanoic acid (CAS 1251222-01-1)
- 2-(But-2-ynyloxy)isonicotinic acid (CAS 1935287-77-6)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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