2-(BROMODIFLUOROMETHYL)-BENZOTHIAZOLE CAS 235781-28-9
| CAS No. | 235781-28-9 |
| Molecular Formula | C8H4BrF2NS |
| Molecular Weight | 264.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(BROMODIFLUOROMETHYL)-BENZOTHIAZOLE (CAS 235781-28-9), molecular formula C8H4BrF2NS and molecular weight 264.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(BROMODIFLUOROMETHYL)-BENZOTHIAZOLE (C8H4BrF2NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(BROMODIFLUOROMETHYL)-BENZOTHIAZOLE meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF2NS |
| Molecular Weight | 264.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2024 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related BROMODIFLUOROMETHYL Standards
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- 4-(Bromodifluoromethyl)-1-(difluoromethyl)-benzene (CAS 2250-36-4)
- 3-(Bromodifluoromethyl)-5-phenyl-1H-pyrazole (CAS 1355046-54-6)
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Recommended Standards
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