5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole CAS 2364584-63-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2364584-63-2
Molecular FormulaC10H7BrFNO
Molecular Weight256.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole CAS 2364584-63-2 chemical structure

Description

The occurrence of 5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole (CAS 2364584-63-2) is a high-purity analytical reference standard with the molecular formula C10H7BrFNO and a molecular weight of 256.07 g/mol.

The molecular framework of 5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole (C10H7BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(2-Bromo-6-fluoro-3-methylphenyl)oxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7BrFNO
Molecular Weight256.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF/Br-containing
Nitrogen Atoms1

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