Ac-Phe-Tyr-OH CAS 2365-53-9
| CAS No. | 2365-53-9 |
| Molecular Formula | C20H22N2O5 |
| Molecular Weight | 370.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ac-Phe-Tyr-OH.
Ac-Phe-Tyr-OH (CAS 2365-53-9), molecular formula C20H22N2O5 and molecular weight 370.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ac-Phe-Tyr-OH (C20H22N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22N2O5 |
| Molecular Weight | 370.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Recommended Standards
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- Ac-Tyr-Phe-OH (CAS 7762-61-0)
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- 1-(2,7-Diazaspiro[4.4]Nonan-2-yl)ethan-1-one hydrochloride (CAS 1808808-99-2)
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