1-(Pyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea CAS 23656-30-6
| CAS No. | 23656-30-6 |
| Molecular Formula | C12H9F3N4O |
| Molecular Weight | 282.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(Pyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 23656-30-6), molecular formula C12H9F3N4O and molecular weight 282.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Pyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (C12H9F3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N4O |
| Molecular Weight | 282.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- (2S,4R,5S)-Lopinavir (CAS 1798014-18-2)
- 6-Chloro-N-(cyclohexylmethyl)pyrimidin-4-amine (CAS 1248091-41-9)
- 1-Bromo-3-((3-fluorophenoxy)methyl)benzene (CAS 1249141-16-9)
- Benzyl -ß-D-Glucopyranosiduronic Acid Methyl Ester Triacetate (CAS 3080-47-5)
- Methyl dodeca-3,6-dienoate (CAS 16106-01-7)
- 4-Nitro-1-propyl-1h-pyrazole-3-carboxylic acid (CAS 1006957-63-6)
- 1-Methyl-1,2,3,4-tetrahydroquinolin-6-ol (CAS 49742-76-9)
- 3-Fluoro-5-hydroxy-4-methoxybenzoic Acid (CAS 1195945-01-7)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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