N-((4,4-difluoro-5-methylpiperidin-3-yl)methyl)methanesulfonamide CAS 2366184-51-0

Purity 97%+In StockPharmaceutical Standards
CAS No.2366184-51-0
Molecular FormulaC8H16F2N2O2S
Molecular Weight242.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-((4,4-difluoro-5-methylpiperidin-3-yl)methyl)methanesulfonamide CAS 2366184-51-0 chemical structure

Description

The occurrence of N-((4,4-difluoro-5-methylpiperidin-3-yl)methyl)methanesulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-((4,4-difluoro-5-methylpiperidin-3-yl)methyl)methanesulfonamide (CAS 2366184-51-0), a certified reference material (molecular formula C8H16F2N2O2S, MW 242.29 g/mol) for analytical method development and quality control.

The molecular framework of N-((4,4-difluoro-5-methylpiperidin-3-yl)methyl)methanesulfonamide (C8H16F2N2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H16F2N2O2S
Molecular Weight242.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1999
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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