Tert-butyl 6,7-dichloro-9-hydroxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate CAS 2369752-69-0
| CAS No. | 2369752-69-0 |
| Molecular Formula | C16H18Cl2N2O3 |
| Molecular Weight | 357.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl 6,7-dichloro-9-hydroxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate.
Tert-butyl 6,7-dichloro-9-hydroxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate (CAS 2369752-69-0) is a high-purity analytical reference standard with the molecular formula C16H18Cl2N2O3 and a molecular weight of 357.23 g/mol.
The molecular framework of Tert-butyl 6,7-dichloro-9-hydroxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate (C16H18Cl2N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl 6,7-dichloro-9-hydroxy-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H18Cl2N2O3 |
| Molecular Weight | 357.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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