Tert-butyl ((3S,5S)-5-(difluoromethyl)piperidin-3-yl)carbamate CAS 2375165-72-1
| CAS No. | 2375165-72-1 |
| Molecular Formula | C11H20F2N2O2 |
| Molecular Weight | 250.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Tert-butyl ((3S,5S)-5-(difluoromethyl)piperidin-3-yl)carbamate (CAS 2375165-72-1), molecular formula C11H20F2N2O2 and molecular weight 250.29 g/mol, is a CATO reference standard with documented purity and traceability.
Tert-butyl ((3S,5S)-5-(difluoromethyl)piperidin-3-yl)carbamate (C11H20F2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Tert-butyl ((3S,5S)-5-(difluoromethyl)piperidin-3-yl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H20F2N2O2 |
| Molecular Weight | 250.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl ((3S,5R)-5-(difluoromethyl)piperidin-3-yl)carbamate (CAS 2375165-88-9)
- Tert-butyl ((4,4-difluoropiperidin-2-yl)methyl)carbamate (CAS 2306270-30-2)
- tert-Butyl ((3R,5S)-5-(difluoromethyl)piperidin-3-yl)carbamate (CAS 2306254-30-6)
- Tert-butyl (2-oxo-3-(pyridin-4-yl)propyl)carbamate (CAS 885269-81-8)
- tert-Butyl 2-(pyridin-3-yl)piperazine-1-carboxylate (CAS 886771-08-0)
- 3-iodo-8-methylquinoline (CAS 1424245-96-4)
- 3-(4-Bromophenyl)pyridine (CAS 129013-83-8)
- 1,3-Benzodioxole-5,6-diamine (CAS 38608-07-0)
- Methyl (R)-3-amino-3-(4-fluoro-2-methylphenyl)propanoate (CAS 1213387-58-6)
- Mosapride Impurity 24 (CAS 483304-07-0)
- 2-(4-Oxo-6-(piperazin-1-yl)quinazolin-3(4H)-yl)acetic acid (CAS 889958-08-1)
- tert-butyl 3-(2-chloroacetyl)azetidine-1-carboxylate (CAS 1260824-43-8)
- 4-Chloro-6-methylnicotinamide (CAS 473255-51-5)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
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