8-chloro-7-fluoro-naphthalen-1-ol CAS 2375588-90-0
| CAS No. | 2375588-90-0 |
| Molecular Formula | C10H16ClFO |
| Molecular Weight | 206.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-chloro-7-fluoro-naphthalen-1-ol.
8-chloro-7-fluoro-naphthalen-1-ol (CAS 2375588-90-0) is a high-purity analytical reference standard with the molecular formula C10H16ClFO and a molecular weight of 206.68 g/mol.
The molecular framework of 8-chloro-7-fluoro-naphthalen-1-ol (C10H16ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-chloro-7-fluoro-naphthalen-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16ClFO |
| Molecular Weight | 206.68 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
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