rel-(1R,2R)-2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid CAS 2375816-30-9
| CAS No. | 2375816-30-9 |
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including rel-(1R,2R)-2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid.
CATO supplies rel-(1R,2R)-2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid (CAS 2375816-30-9), a certified reference material (molecular formula C6H8F2O2, MW 150.12 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, rel-(1R,2R)-2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 150.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rel-(1R,2R)-2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
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