Thalidomide-O-amido-C6-NH2 (hydrochloride) CAS 2376990-31-5
| CAS No. | 2376990-31-5 |
| Molecular Formula | C21H26N4O6 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Thalidomide-O-amido-C6-NH2 (hydrochloride) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Thalidomide-O-amido-C6-NH2 (hydrochloride) (CAS 2376990-31-5) is a high-purity analytical reference standard with the molecular formula C21H26N4O6HCl and a molecular weight of 466.92 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H26N4O6 HCl |
| Molecular Weight | 466.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Thalidomide Standards
- Thalidomide-propargyl-OH (CAS 1216805-67-2)
- Thalidomide-d4 (CAS 1219177-18-0)
- Thalidomide Impurity 3 (CAS 126663-38-5)
- Thalidomide-5,6-F (CAS 1496997-41-1)
- Thalidomide-O-amido-C4-NH2 (CAS 1799711-24-2)
- Thalidomide-O-amido-C3-PEG3-C1-NH2 (CAS 1799711-29-7)
- Thalidomide-O-amido-C6-NH2 (CAS 1950635-13-8)
- Thalidomide-O-amido-C6-NH2 (TFA) (CAS 1950635-14-9)
Recommended Standards
- 2,5-Dimethyl-4-(methylthio)benzaldehyde (CAS 2586125-80-4)
- 5-(Ethoxymethyl)pyridine-3-boronic acid (CAS 723281-60-5)
- 1,2-Bis(4-methoxybenzylidene)hydrazine (CAS 2299-73-2)
- N-Alpha-benzoyl-L-arginine methyl ester HCl (CAS 1784-04-9)
- 5-Cyclopropoxy-2-ethyl-N,N-dimethylbenzamide (CAS 1243475-38-8)
- 3-(1,2,3,4-Tetrahydroquinolin-4-yl)propanoic acid (CAS 102586-93-6)
- 4-Bromo-2-(((3-methylbenzo[d]thiazol-2(3H)-ylidene)hydrazineylidene)methyl)phenol (CAS 364623-18-7)
- 4,5-Dibromo-2,3-difluorophenylacetonitrile (CAS 1806350-91-3)
- Pesticide Mix 19 (CAS CATO-MCPD190748-A)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
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