5-Bromo-4-chloro-2-fluoro-3-methylphenylboronic acid CAS 2377606-52-3
| CAS No. | 2377606-52-3 |
| Molecular Formula | C7H6BBrClFO2 |
| Molecular Weight | 267.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Bromo-4-chloro-2-fluoro-3-methylphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-Bromo-4-chloro-2-fluoro-3-methylphenylboronic acid (CAS 2377606-52-3), a certified reference material (molecular formula C7H6BBrClFO2, MW 267.29 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-4-chloro-2-fluoro-3-methylphenylboronic acid (C7H6BBrClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6BBrClFO2 |
| Molecular Weight | 267.29 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
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- 4-Bromo-1-(cyclohexylmethyl)-2-methylbenzene (CAS 1369886-55-4)
- 5-(3-Bromo-2,2-dimethylpropyl)-2,3-dihydro-1h-indene (CAS 1465912-94-0)
- 1-Bromo-4-(1-cyclohexylethyl)benzene (CAS 1892735-90-8)
Recommended Standards
- 5-Amino-2-ethyl-7-(pyridin-4-yl)-1,7-dihydropyrano[2,3-d]imidazole-6-carbonitrile (CAS 374612-98-3)
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- N-(4-(2-Methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl)acetamide (CAS 611239-38-4)
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- 2-(3-(Pyridin-3-yl)-5-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1214378-50-3)
- 5-(bromomethyl)-3-(4-chlorophenyl)-1,3-oxazolidin-2-one (CAS 104392-63-4)
- (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-(benzyloxy)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 35638-82-5)
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