tert-Butyl 4-bromo-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate CAS 2377606-76-1
| CAS No. | 2377606-76-1 |
| Molecular Formula | C19H25BBrNO4 |
| Molecular Weight | 422.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 422.12 g/mol gives tert-Butyl 4-bromo-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl 4-bromo-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate (CAS 2377606-76-1), molecular formula C19H25BBrNO4 and molecular weight 422.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, tert-Butyl 4-bromo-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate (C19H25BBrNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 422.12 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H25BBrNO4 |
| Molecular Weight | 422.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3-((4-Bromophenyl)sulfonyl)-1-(3,4-dichlorophenyl)propan-1-one (CAS 477334-45-5)
- Tert-butyl 6-bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (CAS 870099-01-7)
- Tert-butyl 4-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (CAS 1256360-01-6)
- tert-Butyl 7-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (CAS 2173192-44-2)
- (2S,3S,4R,5R,6R)-3-(Allyloxy)-6-(benzyloxy)-4,5-dimethoxy-2-methyltetrahydro-2H-pyran (CAS 114284-04-7)
- 6-(Piperidin-4-yl)pyridazin-3-ol (CAS 1824129-12-5)
- (1-(2,3-Difluorophenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 1249833-86-0)
- 7-N-benzyl-[1,3]diazino[4,5-d]pyrimidine-2,4,7-triamine (CAS 109160-46-5)
- 2-(3,3-Difluorocyclopentyl)acetic acid (CAS 1260837-43-1)
- 4-(Azetidin-3-yl)-1-methylpiperidine (CAS 1511174-81-4)
- 14-Acetyloxycodone (1.0mg/ml in Acetonitrile) (CAS 70509-92-1)
- 3-(5,6-Dihydro-4H-cyclopenta[d]isoxazol-3-yl)propanal (CAS 181059-25-6)
- Ethyl 4-methylisoxazole-3-carboxylate (CAS 38061-69-7)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com