3-Bromo-5-chlorothiophene-2-boronic acid CAS 2377609-99-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2377609-99-7
Molecular FormulaC4H3BBrClO2S
Molecular Weight241.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Bromo-5-chlorothiophene-2-boronic acid CAS 2377609-99-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 241.30 g/mol gives 3-Bromo-5-chlorothiophene-2-boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Bromo-5-chlorothiophene-2-boronic acid (CAS 2377609-99-7) is a high-purity analytical reference standard with the molecular formula C4H3BBrClO2S and a molecular weight of 241.30 g/mol.

Based on its molecular formula C4H3BBrClO2S, 3-Bromo-5-chlorothiophene-2-boronic acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 241.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Bromo-5-chlorothiophene-2-boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H3BBrClO2S
Molecular Weight241.30 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.5
CAS Registry Year (est.)1999
Halogen ContentCl/Br-containing
Sulfur Atoms1

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