2-Propoxy-4-(trifluoromethyl)phenylboronic acid CAS 2377611-21-5

Purity 97%+In StockPharmaceutical Standards
CAS No.2377611-21-5
Molecular FormulaC10H12BF3O3
Molecular Weight248.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Propoxy-4-(trifluoromethyl)phenylboronic acid CAS 2377611-21-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 248.01 g/mol gives 2-Propoxy-4-(trifluoromethyl)phenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Propoxy-4-(trifluoromethyl)phenylboronic acid (CAS 2377611-21-5), a certified reference material (molecular formula C10H12BF3O3, MW 248.01 g/mol) for analytical method development and quality control.

2-Propoxy-4-(trifluoromethyl)phenylboronic acid (C10H12BF3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Propoxy-4-(trifluoromethyl)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H12BF3O3
Molecular Weight248.01 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1999
Halogen ContentF-containing

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