4-(1-Cyano-1-methylethyl)-3-fluorophenylboronic acid CAS 2377611-26-0
| CAS No. | 2377611-26-0 |
| Molecular Formula | C10H11BFNO2 |
| Molecular Weight | 207.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(1-Cyano-1-methylethyl)-3-fluorophenylboronic acid (CAS 2377611-26-0), a certified reference material (molecular formula C10H11BFNO2, MW 207.01 g/mol) for analytical method development and quality control.
The molecular framework of 4-(1-Cyano-1-methylethyl)-3-fluorophenylboronic acid (C10H11BFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 4-(1-Cyano-1-methylethyl)-3-fluorophenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11BFNO2 |
| Molecular Weight | 207.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyano Standards
- 4-(1-Cyano-1-methylethyl)-2-fluorophenylboronic acid (CAS 1793003-65-2)
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- Methyl 5-cyano-2-hydroxy-4-methoxybenzoate (CAS 1803772-62-4)
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Recommended Standards
- 3-Amino-2,6-dichloroisonicotinic Acid (CAS 58484-01-8)
- 4,5-Dichloro-2,3-dihydroxybenzaldehyde (CAS 73275-97-5)
- 3,6-Dichloro-5-methylpyrazine-2-carboxylic acid (CAS 72876-12-1)
- 4,5-Dichloro-2-hydroxybenzoic acid (CAS 50274-58-3)
- 3-(2,5-difluorophenyl)-1-methyl-1H-pyrazole-4-carboxylic acid (CAS 1152548-65-6)
- Methyl 2-(1-ethyl-1h-pyrazol-5-yl)-2-hydroxyacetate (CAS 1481774-46-2)
- 2-(4-Fluoro-6-(trifluoromethyl)pyridin-2-yl)ethan-1-amine (CAS 1393543-34-4)
- Ethyl 3-phenylpiperazine-1-carboxylate (CAS 904814-49-9)
- Methyl 4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzoate (CAS 721961-57-5)
- 2-Amino-1-(3-chlorothiophen-2-yl)ethan-1-one (CAS 538328-12-0)
- (R)-2-((1-Acetylpiperidin-3-yl)oxy)acetic acid (CAS 1353992-67-2)
- 2-Chloro-N-(1-methoxypropan-2-yl)-4-methylaniline (CAS 1247356-68-8)
- (2R,3R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-3-(naphthalen-1-yl)propanoic acid (CAS 1217649-42-7)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com