1-Ethynyl-4-fluorobenzene-2,3,5,6-d4 CAS 2378754-22-2
| CAS No. | 2378754-22-2 |
| Molecular Formula | - |
| Molecular Weight | 124.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-Ethynyl-4-fluorobenzene-2,3,5,6-d4 (CAS 2378754-22-2) is a high-purity analytical reference standard with the molecular formula C8HD4F and a molecular weight of 124.15 g/mol.
The molecular framework of 1-Ethynyl-4-fluorobenzene-2,3,5,6-d4 (C8HD4F) is characterized by deuterium isotope labeling, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8HD4F |
| Molecular Weight | 124.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
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- 2-[[5-(1-Methylethyl)-1,3,4-thiadiazol-2-yl]amino]-2-oxoacetic acid (CAS 1158206-46-2)
- 6-(Difluoromethyl)-4-(1,5-dimethyl-1H-pyrazol-4-yl)-2-mercaptonicotinonitrile (CAS 1001519-35-2)
- 6-Iodo-9-(tetrahydrothiophen-2-yl)-9H-purine (CAS 90347-61-8)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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