3-Chloro-2-(o-tolyl)pyridine CAS 2379321-40-9
| CAS No. | 2379321-40-9 |
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-2-(o-tolyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Chloro-2-(o-tolyl)pyridine (CAS 2379321-40-9) is a high-purity analytical reference standard with the molecular formula C12H10ClN and a molecular weight of 203.67 g/mol.
The molecular framework of 3-Chloro-2-(o-tolyl)pyridine (C12H10ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-phenylaniline (CAS 101-17-7)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- 2-Chloro-4-(4-methylphenyl)pyridine (CAS 1202574-24-0)
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- 2'-Chloro-[1,1'-biphenyl]-4-amine (CAS 1204-42-8)
- 2-Chloro-4-methyl-5-phenylpyridine (CAS 1214335-53-1)
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- 4-chloro-5,5-dimethyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one (CAS 1226804-02-9)
Recommended Standards
- 3-chloro-1-methoxy-5,6-dihydrocyclopenta[c]pyridin-7-one (CAS 2747098-69-5)
- 3-Chloro-2-(p-tolyl)pyridine (CAS 892482-36-9)
- 3'-Chloro-[1,1'-biphenyl]-4-amine (CAS 5748-36-7)
- 3-Chloro-biphenyl-4-ylamine (CAS 7285-66-7)
- 6-(Methylamino)-2-phenylpyrimidine-4-carboxamide (CAS 1281872-50-1)
- 3-Bromo-2-methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 1399662-89-5)
- 1-Benzyl 2-methyl (2R)-5-oxopyrrolidine-1,2-dicarboxylate (CAS 690211-34-8)
- N-(2-Fluorophenyl)-5-pyrrolidin-2-yl-1,3,4-thiadiazole-2-carboxamide (CAS 1217885-75-0)
- 2-[(4-Ethylbenzoyl)amino]-3-methylbutanoic acid (CAS 1396964-80-9)
- 4-(4-Methoxyphenyl)-2-(5-phenyl-1H-pyrazol-1-yl)-1,3-thiazole (CAS 956369-95-2)
- 2-Chloro-N-(1-(2,4-dichlorobenzyl)-1H-pyrazol-3-yl)acetamide (CAS 1004643-27-9)
- 2-Methyl-propanoic Acid 3-Hydroxy-2,2,4-trimethylpentyl Ester (CAS 77-68-9)
- (5-Acetyl-4-chlorofuran-2-yl)methyl acetate (CAS 96328-19-7)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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