1-Ethoxy-3,4-difluoro-2-methoxybenzene CAS 2379321-67-0

Purity 97%+In StockPharmaceutical Standards
CAS No.2379321-67-0
Molecular FormulaC9H10F2O2
Molecular Weight188.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Ethoxy-3,4-difluoro-2-methoxybenzene CAS 2379321-67-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 188.17 g/mol gives 1-Ethoxy-3,4-difluoro-2-methoxybenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Ethoxy-3,4-difluoro-2-methoxybenzene (CAS 2379321-67-0), molecular formula C9H10F2O2 and molecular weight 188.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Ethoxy-3,4-difluoro-2-methoxybenzene (C9H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Ethoxy-3,4-difluoro-2-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H10F2O2
Molecular Weight188.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF-containing

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