1-(Benzyloxy)-4-bromo-3-chloro-2-methylbenzene CAS 2379321-81-8
| CAS No. | 2379321-81-8 |
| Molecular Formula | C14H12BrClO |
| Molecular Weight | 311.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(Benzyloxy)-4-bromo-3-chloro-2-methylbenzene (C14H12BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1-(Benzyloxy)-4-bromo-3-chloro-2-methylbenzene (CAS 2379321-81-8), a certified reference material (molecular formula C14H12BrClO, MW 311.60 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Benzyloxy)-4-bromo-3-chloro-2-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12BrClO |
| Molecular Weight | 311.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl/Br-containing |
Related Benzyloxy Standards
- 1-(Benzyloxy)-4-bromo-2-chloro-3-methylbenzene (CAS 2379321-72-7)
- 1-(Benzyloxy)-4-bromo-5-chloro-2-methylbenzene (CAS 2379321-31-8)
- 1-(Benzyloxy)-6-bromo-2-chloro-3-methylbenzene (CAS 2244107-79-5)
- 4-(Benzyloxy)-6-formylpyridine-2-sulfonyl chloride (CAS 1393558-85-4)
- 3-((Benzyloxy)methyl)-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1151649-92-1)
- 8-(Benzyloxy)-2-phenylquinoline (CAS 687637-87-2)
- (5E)-5-{[4-(benzyloxy)phenyl]methylidene}-1,3-thiazolidine-2,4-dione (CAS 262844-52-0)
- Ethyl 2-(benzyloxy)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 162286-96-6)
Recommended Standards
- (2-Bromophenyl)(3-chloro-2-methylphenyl)methanol (CAS 1443351-97-0)
- (4-Bromophenyl)(5-chloro-2-methylphenyl)methanol (CAS 1443351-90-3)
- 4-bromo-1-[(3-chlorophenyl)methoxy]-2-methylbenzene (CAS 854259-18-0)
- (2-Bromophenyl)(4-chloro-2-methylphenyl)methanol (CAS 1443351-61-8)
- 1-(4-Isopropylphenyl)propan-1-amine hydrochloride (CAS 1197236-36-4)
- 2-Bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)ethan-1-one (CAS 1311569-68-2)
- (E)-N,N-bis(2-Hydroxyethyl)-Oleylamine (CAS 25307-17-9)
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinaldehyde (CAS 1309982-40-8)
- 4-Methoxy-2-methyl-butane-2-thiol (CAS 94087-83-9)
- (1R,3aS,6aR)-2-(tert-Butoxycarbonyl)octahydrocyclopenta[c]pyrrole-1-carboxylic acid (CAS 1393524-06-5)
- 6-bromopyrrolo[2,1-f][1,2,4]triazine-2,4-diamine (CAS 1824200-86-3)
- 2-Propenoic acid, 2-methyl-, (S)-tetrahydro-5-oxo-3-furanyl ester (CAS 521291-57-6)
- Methyl 5-fluoro-2-methoxyisonicotinate (CAS 1214346-01-6)
- C-Peptide 1 (rat) (CAS 41475-27-8)
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