2-Chloro-N-((dimethylamino)methylene)-4-fluorobenzamide CAS 2379917-15-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2379917-15-2
Molecular FormulaC10H10ClFN2O
Molecular Weight228.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N-((dimethylamino)methylene)-4-fluorobenzamide CAS 2379917-15-2 chemical structure

Description

The occurrence of 2-Chloro-N-((dimethylamino)methylene)-4-fluorobenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Chloro-N-((dimethylamino)methylene)-4-fluorobenzamide (CAS 2379917-15-2), a certified reference material (molecular formula C10H10ClFN2O, MW 228.65 g/mol) for analytical method development and quality control.

2-Chloro-N-((dimethylamino)methylene)-4-fluorobenzamide (C10H10ClFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10ClFN2O
Molecular Weight228.65 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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