4,5-Dichloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6-methylpyrimidine CAS 2379918-50-8
| CAS No. | 2379918-50-8 |
| Molecular Formula | C11H5Cl3F3N3 |
| Molecular Weight | 342.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4,5-Dichloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6-methylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4,5-Dichloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6-methylpyrimidine (CAS 2379918-50-8) is a high-purity analytical reference standard with the molecular formula C11H5Cl3F3N3 and a molecular weight of 342.53 g/mol.
The molecular framework of 4,5-Dichloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6-methylpyrimidine (C11H5Cl3F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H5Cl3F3N3 |
| Molecular Weight | 342.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 3,5-Dimethyl-1H-pyrazole-1-carbothioic dithioperoxyanhydride (CAS 473804-86-3)
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- 7-Iodobenzofuran-5-sulfonylchloride (CAS 856678-58-5)
- 5-(chloromethyl)-3-(2-phenylethyl)-1,2,4-oxadiazole (CAS 1247725-97-8)
- 4-oxobutanenitrile (CAS 3515-93-3)
- 4-Fluorobenzothiohydrazide 2,2,2-Trifluoroacetate (CAS 863296-74-6)
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- 4-Phenyl-1,3-oxazole-2-carbaldehyde (CAS 1199623-97-6)
- Obeticholic Acid Impurity 14 (CAS CATO-C4X-115314)
- 2-(4-Methoxyphenyl)-1-(2,7-diazaspiro[3.5]Nonan-7-yl)ethan-1-one (CAS 1206969-60-9)
- 4-(4-Bromo-2,5-difluorophenoxy)butanenitrile (CAS 1443337-15-2)
- 1-(3-carboxypropyl)-11-ethyl-1,2,3,4,8,9,10,11-octahydro-dipyrido[3,2-b:2',3'-i]phenoxazin-13-ium 185308-24-1 MR 121 MR 121 Cation (CAS 185308-24-1)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com