Tert-butyl (r)-3-(4-amino-3-fluorophenoxy)pyrrolidine-1-carboxylate CAS 2380449-71-6
| CAS No. | 2380449-71-6 |
| Molecular Formula | C15H21FN2O3 |
| Molecular Weight | 296.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl (r)-3-(4-amino-3-fluorophenoxy)pyrrolidine-1-carboxylate.
CATO supplies Tert-butyl (r)-3-(4-amino-3-fluorophenoxy)pyrrolidine-1-carboxylate (CAS 2380449-71-6), a certified reference material (molecular formula C15H21FN2O3, MW 296.34 g/mol) for analytical method development and quality control.
Structurally, Tert-butyl (r)-3-(4-amino-3-fluorophenoxy)pyrrolidine-1-carboxylate (C15H21FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 296.34 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H21FN2O3 |
| Molecular Weight | 296.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-Acetyl-N-(4-(methylsulfinyl)phenyl)oxazolidine-2-carboxamide (CAS 96800-41-8)
- Tert-butyl (s)-3-(4-amino-3-fluorophenoxy)pyrrolidine-1-carboxylate (CAS 2382500-35-6)
- N-(benzofuran-5-ylcarbamothioyl)benzamide (CAS 866017-44-9)
- Tert-butyl 4-(3-fluoro-4-hydroxyphenyl)piperazine-1-carboxylate (CAS 742067-14-7)
- (S)-3-Methyl-5-(pyrrolidin-2-yl)isoxazole (CAS 147402-52-6)
- 2,3-Dihydrobenzo[b][1,4]dioxine-2-sulfonyl chloride (CAS 499770-80-8)
- Ethyl 4-(dimethylamino)-5,8-difluoroquinoline-3-carboxylate (CAS 1315353-23-1)
- 4,4'-Oxybis(2-nitroaniline) (CAS 3273-78-7)
- 1-Methoxy-4-(2-methylprop-1-en-1-yl)benzene (CAS 877-99-6)
- (3aR,3'aR,8aS,8'a'S)-2,2'-Cyclopropylidenebis[3a,8a-dihydro-8H-Indeno[1,2-d]oxazole] (CAS 229184-98-9)
- 1-(4-Fluoro-2-(methylsulfonyl)phenyl)piperazine (CAS 849938-78-9)
- Des-Arg Cetrorelix Acetate (CAS CATO-C4X-20148)
- 4-(2-Fluorophenyl)-3-methyl-1H-pyrazol-5-amine hydrochloride (CAS 1257878-84-4)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
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