(3R,4R,5R,6R)-5-fluoro-6-(fluoromethyl)tetrahydro-2H-pyran-2,3,4-triol CAS 238403-53-7

Description

The occurrence of (3R,4R,5R,6R)-5-fluoro-6-(fluoromethyl)tetrahydro-2H-pyran-2,3,4-triol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(3R,4R,5R,6R)-5-fluoro-6-(fluoromethyl)tetrahydro-2H-pyran-2,3,4-triol (CAS 238403-53-7) is a high-purity analytical reference standard with the molecular formula C6H10F2O4 and a molecular weight of 184.14 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (3R,4R,5R,6R)-5-fluoro-6-(fluoromethyl)tetrahydro-2H-pyran-2,3,4-triol is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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