1-(4-Amino-2-fluoro-3-methoxyphenyl)ethan-1-one CAS 2385127-37-5
| CAS No. | 2385127-37-5 |
| Molecular Formula | C9H10FNO2 |
| Molecular Weight | 183.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-Amino-2-fluoro-3-methoxyphenyl)ethan-1-one (C9H10FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(4-Amino-2-fluoro-3-methoxyphenyl)ethan-1-one (CAS 2385127-37-5), molecular formula C9H10FNO2 and molecular weight 183.18 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Amino-2-fluoro-3-methoxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10FNO2 |
| Molecular Weight | 183.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- methyl 2-amino-4-fluoro-5-methylbenzoate (CAS 1037206-86-2)
- 2-Amino-2-(2-fluoro-4-methylphenyl)acetic acid (CAS 1039118-67-6)
- 2-Amino-2-(5-fluoro-2-methylphenyl)acetic acid (CAS 1039365-71-3)
- 2-Amino-2-(4-fluoro-2-methylphenyl)acetic acid (CAS 1039620-35-3)
- 1-(2-amino-3-fluoro-4-methoxyphenyl)ethan-1-one (CAS 1073119-05-7)
- Methyl 3-amino-5-fluoro-4-methylbenzoate (CAS 1093087-06-9)
- Ethyl 2-amino-6-fluorobenzoate (CAS 1108668-11-6)
- Ethyl 2-amino-4-fluorobenzoate (CAS 117324-05-7)
Recommended Standards
- 1-(2-Amino-4-fluoro-5-methoxyphenyl)ethan-1-one (CAS 949159-97-1)
- 1-Amino-2-methyl-1-oxopropan-2-yl hydrogen sulfate (CAS 49562-37-0)
- (S)-N-(1-(5-fluoropyrimidin-2-yl)ethyl)acetamide (CAS 905587-31-7)
- 1-Fluoro-3,4,5-trimethyl-2-nitrobenzene (CAS 62622-61-1)
- Salicylic Acid Mix 5 (CAS CATO-MCHM702009-ME)
- 5-Ethyl-4-(3-fluorophenyl)-4H-1,2,4-triazole-3-thiol (CAS 669745-81-7)
- 1-[2-(2-chlorophenoxy)ethyl]-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 1423026-82-7)
- 4-(((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)amino)-4-oxobutanoic acid (CAS 337497-09-3)
- 4-(4-(Difluoromethoxy)phenyl)piperidine (CAS 1211530-65-2)
- 1-Cyclopropoxy-3-methylbenzene (CAS 18928-87-5)
- Atorvastatin Impurity N4 (CAS 62148-67-8)
- N1-(2-(1-Ethyl-1,2,3,4-tetrahydroquinolin-6-yl)ethyl)-N2-isopropyloxalamide (CAS 955531-52-9)
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carboxamide (CAS 321432-70-6)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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