(2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol CAS 2385292-41-9
| CAS No. | 2385292-41-9 |
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol.
(2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol (CAS 2385292-41-9), molecular formula C8H6BrF3O and molecular weight 255.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol (C8H6BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2-Bromo-3-(difluoromethyl)-4-fluorophenyl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene (CAS 106854-77-7)
- (2-Bromo-3-(trifluoromethyl)phenyl)methanol (CAS 1214330-94-5)
- 1-Bromo-3-methoxy-2-(trifluoromethyl)benzene (CAS 1214345-25-1)
- (5-Bromo-2-(trifluoromethyl)phenyl)methanol (CAS 1214349-54-8)
- (2-Bromo-6-(trifluoromethyl)phenyl)methanol (CAS 1214350-24-9)
- 4-Bromo-1-methoxy-2-(trifluoromethyl)benzene (CAS 1514-11-0)
- 1-Bromo-3-(2,2-difluoroethoxy)-5-fluorobenzene (CAS 1538752-02-1)
- (3-Bromo-5-(trifluoromethyl)phenyl)methanol (CAS 172023-97-1)
Recommended Standards
- 2-Bromo-3-methyl-5-(trifluoromethyl)phenol (CAS 1934389-15-7)
- (3-Bromo-4-(trifluoromethyl)phenyl)methanol (CAS 372120-54-2)
- 2-(4-Bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol (CAS 1823989-97-4)
- (R)-1-(4-Bromophenyl)-2,2,2-trifluoroethanol (CAS 80418-12-8)
- Fema3952 (CAS 68555-65-7)
- 2-(3-Cyanophenoxy)acetamide (CAS 902094-93-3)
- 2,4,6-Tri-tert-butyl pyrimidine 67490-21-5 2,4,6-Tri-tert-butylpyrimidine;2,4,6-Tri-tert-butylpyrimidine (CAS 67490-21-5)
- (S)-Pramipexole-(N-Propyl-2,2,3,3,3-d5) Dihydrochloride (CAS 1217601-58-5)
- Cefuroxime Axetil Impurity 16 (CAS CATO-C4X-143616)
- 3-(((4-Chlorobenzyl)thio)methyl)-5-((4-methylbenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 344269-47-2)
- Bromuconazole (CAS 116255-48-2)
- 2-Fluoro-5-isopropoxynicotinic acid (CAS 1370025-60-7)
- 3-Methyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione (CAS 737697-00-6)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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