2-Fluoro-4-methyl-5-(trifluoromethyl)benzoic acid CAS 2385359-85-1
| CAS No. | 2385359-85-1 |
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Fluoro-4-methyl-5-(trifluoromethyl)benzoic acid (C9H6F4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 222.14 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Fluoro-4-methyl-5-(trifluoromethyl)benzoic acid (CAS 2385359-85-1), a certified reference material (molecular formula C9H6F4O2, MW 222.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 1-(4-Fluoro-3-(trifluoromethyl)phenyl)urea (CAS 1000588-77-1)
- 3-fluoro-2-methyl-4-(trifluoromethyl)benzoic acid (CAS 1070761-76-0)
- 2-Fluoro-5-(trifluoromethyl)benzohydrazide (CAS 1079843-54-1)
- 1-(3-Fluoro-4-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1174006-08-6)
- 2-Fluoro-5-methyl-4-(trifluoromethyl)benzoic acid (CAS 1323955-61-8)
- 2-Fluoro-3-methoxy-4-(trifluoromethyl)benzaldehyde (CAS 1352719-37-9)
- 1-(3-Fluoro-5-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1352999-53-1)
- 4-Fluoro-3-methyl-5-(trifluoromethyl)benzoic acid (CAS 1373920-63-8)
Recommended Standards
- 2-Fluoro-4-methoxy-5-(trifluoromethyl)benzaldehyde (CAS 2183512-39-0)
- 2-Fluoro-5-(trifluoromethyl)phenylacetic Acid (CAS 220227-66-7)
- 2-Fluoro-4-(trifluoromethyl)phenylacetic Acid (CAS 209991-64-0)
- 2-Fluoro-6-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 907609-06-7)
- 4-Cyclopropoxy-6-methoxynicotinonitrile (CAS 1243354-92-8)
- Ethyl 4-phenyl-3-ketobutanoate, 97% (CAS 718-08-1)
- phenylsulfonylmethylisocyanide (CAS 36635-63-9)
- 3-((4-Chloro-1H-pyrazol-1-yl)methoxy)benzaldehyde (CAS 1006460-35-0)
- 5-Bromo-1H-indazol-4-ol (CAS 1638763-63-9)
- (5-(Pyridin-3-yloxy)furan-2-yl)methanol (CAS 857284-15-2)
- 2-methyl-5-phenylpentanoic acid (CAS 143097-60-3)
- Potassium (2-bromophenylsulfonamido)methyltrifluoroborate (CAS 1286686-28-9)
- Methyl 4-(Bromomethyl)-3-chlorobenzoate (CAS 74733-30-5)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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