(5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine CAS 2386111-72-2
| CAS No. | 2386111-72-2 |
| Molecular Formula | C8H6BrF4N |
| Molecular Weight | 272.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 272.04 g/mol gives (5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine (CAS 2386111-72-2), a certified reference material (molecular formula C8H6BrF4N, MW 272.04 g/mol) for analytical method development and quality control.
(5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine (C8H6BrF4N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF4N |
| Molecular Weight | 272.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-fluoro-N-(2,2,2-trifluoroethyl)aniline (CAS 1021125-31-4)
- 2-Bromo-4-fluoro-N-(2,2,2-trifluoroethyl)aniline (CAS 1039963-64-8)
- (S)-1-(5-Bromo-2-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212881-54-3)
- (R)-1-(4-Bromo-3-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213384-22-5)
- (R)-1-(5-Bromo-2-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213389-71-9)
- 1-(5-Bromo-2-fluorophenyl)-2,2,2-trifluoroethylamine (CAS 1270452-52-2)
- (6-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)methanamine (CAS 1352718-91-2)
- (2-Bromo-4-fluoro-6-(trifluoromethyl)phenyl)methanamine (CAS 2385725-83-5)
Recommended Standards
- (3-Bromo-6-fluoro-2-(trifluoromethyl)phenyl)methanamine (CAS 2385185-07-7)
- 2-(3-Iodophenyl)-1,3,4-oxadiazole (CAS 31822-06-7)
- (3-Bromo-2-fluoro-5-(trifluoromethyl)phenyl)methanamine (CAS 871325-57-4)
- 2,3-Dichloro-5-nitro-1,4-naphthoquinone (CAS 22360-86-7)
- 3-(2-Fluoropyridin-3-yl)propanoic acid (CAS 944998-14-5)
- 2-(4-Cyclohexylphenoxy)acetic acid (CAS 1878-56-4)
- 4-[(Boc-amino)methyl]aniline Hydrochloride (CAS 174959-54-7)
- 4-Propoxybenzo[b]thiophene-6-carboxylic acid (CAS 1291492-28-8)
- 7-bromo-6-methyl-imidazo[1,2-a]pyridine (CAS 2089158-09-6)
- [3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methanol (CAS 36640-54-7)
- Cycloheptanecarboximidamide (CAS 885964-25-0)
- 2'-Chloroacetoacetanilide (CAS 93-70-9)
- tert-Butyl N-[3-(aminomethyl)bicyclo[1.1.1]pentan-1-yl]carbamate (CAS 1638765-05-5)
- Insulin Glulisine (CAS 207748-29-6)
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