2-Fluoro-6-methoxy-3-nitrobenzoic acid CAS 2386633-76-5
| CAS No. | 2386633-76-5 |
| Molecular Formula | C8H6FNO5 |
| Molecular Weight | 215.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Fluoro-6-methoxy-3-nitrobenzoic acid (CAS 2386633-76-5), a certified reference material (molecular formula C8H6FNO5, MW 215.14 g/mol) for analytical method development and quality control.
2-Fluoro-6-methoxy-3-nitrobenzoic acid (C8H6FNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6FNO5 |
| Molecular Weight | 215.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-3-methoxy-2-nitrobenzoic acid (CAS 1007113-04-3)
- 3-Fluoro-5-methoxy-4-nitrobenzoic acid (CAS 1137869-93-2)
- 3-Fluoro-2-methyl-4,6-dinitro-phenylamine (CAS 1167056-65-6)
- 2-(3-Fluoro-5-nitrophenyl)-2-hydroxyacetic acid (CAS 1214372-84-5)
- 2-(3-Fluoro-4-nitrophenyl)-2-hydroxyacetic acid (CAS 1214385-61-1)
- Methyl 4-fluoro-2-hydroxy-3-nitrobenzoate (CAS 1263283-00-6)
- Methyl 2-fluoro-5-hydroxy-3-nitrobenzoate (CAS 1394977-92-4)
- Methyl 4-fluoro-5-hydroxy-2-nitrobenzoate (CAS 1426958-40-8)
Recommended Standards
- 2,4-Diamino-3-fluoro-5-nitrobenzoic acid (CAS 918321-31-0)
- 3-Fluoro-4-methoxy-5-nitrobenzoic acid (CAS 577-39-9)
- 2-(5-Fluoro-2-nitrophenoxy)acetic acid (CAS 396-03-2)
- 3-Nitrophenyl dimethylphosphinate (CAS 59581-57-6)
- N,1-dimethyl-6-morpholino-3,5-dinitro-1,4-dihydropyridin-2-amine (CAS 338777-82-5)
- 3-Fluoro-4-nitro-o-xylene (CAS 3013-30-7)
- Valganciclovir N-Valyl Impurity (CAS 897937-73-4)
- Emtricitabine Impurity 28 (CAS CATO-C4X-123228)
- Aristolochic acid I (CAS 10190-99-5)
- Fumarate Impurity 3 (CAS 132475-93-5)
- Sodium 3,3'-(dodecylazanediyl)dipropionate (CAS 3655-00-3)
- 7-Amino-4-methyl-2H-chromen-2-one sulfate (CAS 207673-94-7)
- Chitohexaose 6HCl (CAS 41708-95-6 (free base))
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com