Labetalol EP Impurity C HCl CAS 2386661-13-6
| CAS No. | 2386661-13-6 |
| Molecular Formula | C16H18N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 322.79 g/mol gives Labetalol EP Impurity C HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Labetalol EP Impurity C HCl (CAS 2386661-13-6), a pharmacopoeial impurity reference standard (molecular formula C16H18N2O3HCl, MW 322.79 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Labetalol EP Impurity C HCl (C16H18N2O3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O3 HCl |
| Molecular Weight | 322.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Labetalol Standards
- Labetalol Impurity 29 (CAS 119021-71-5)
- Labetalol EP Impurity A (CAS 1391051-99-2)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Labetalol-d5 HCl (CAS 2713514-78-2)
- Labetalol Impurity 23 (CAS 2724509-52-6)
- Labetalol Impurity 56 (CAS 2731858-23-2)
- Labetalol EP Impurity D HCl (CAS 32780-65-7)
- Labetalol Impurity 21 (CAS 33254-88-5)
Recommended Standards
- Acotiamide Impurity 10 (CAS CATO-C4X-111410)
- Venetoclax Impurity 74 (CAS CATO-C4X-249574)
- Dronedarone Impurity 57 (CAS 98873-72-4)
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- (1-Methyl-1H-pyrrol-2-yl)boronic acid (CAS 911318-81-5)
- 2-(4-Chlorobenzoyl)-6-methoxypyridine (CAS 1187171-01-2)
- 14-(3-(Methylsulfonamido)propyl)-7-phenyl-5,6,8,9-tetrahydrodibenzo[c,h]acridin-14-ium trifluoromethanesulfonate (CAS 457602-06-1)
- 3,4-Dimethylmethcathinone hydrochloride (CAS 1081772-06-6)
- N-(3,5-Dimethylphenyl)-2-(2-methyl-3,5-dioxothiomorpholino)acetamide (CAS 868215-88-7)
- Mitogenic Pentapeptide (CAS 87173-03-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com